Description

A postdoctoral research position is immediately available in the Grimes laboratory (@LeeGrimesLab) at Cincinnati Children's Hospital, in Cincinnati Ohio (an affordable metro area of more than 2 million people, with access to the arts, great restaurants, excellent schools and parks).

Dual training in hematology/oncology and informatics (with @nsalomonis). The lab exploits cutting-edge omics tech to answer fundamental biological questions in hematopoiesis, marrow failure and myeloid leukemia. We develop new informatics tools when existing tools are insufficient to resolve the data. For example: PMID: 32494068, PMID: 30249787, PMID: 30243574, PMID: 29977015 and PMID: 27580035.

Cincinnati Children's Hospital Medical Center (CCHMC) is an academic pediatric acute care children's hospital with 634 pediatric beds which serves patients from 51 countries and 50 US states. CCHMC ranks third in 2019-2020 and 2020-2021 by US News and World Report, and receives the third-most NIH funds of any pediatric institution in the United States. CCHMC's research mission is aided by a $3 billion endowment, which subsidizes state-of-the-art core facilities with career technicians for marrow transplant, single cell processing, flow cytometry, computational biology, etc. The training environment is especially rich for hematology/oncology research because of a robust and interactive research community.

REPRESENTATIVE RESPONSIBILITIES

1. Design, execute, and record laboratory experiments; apply standard scientific protocols to experiments, research, and improve current methods and evaluate innovative techniques.
2. Draft, write, and edit scientific reports, papers, journal articles, and abstracts.
3. Design and perform experiments and record data according to research protocol. Independently reproduce, evaluate, research, and improve techniques currently used. Adapt new methods to existing procedures and modify current experiments through scientific knowledge and intuition. Maintain accurate and detailed records of all laboratory work and experiments.
4. Develop, set-up, and verify new procedures in the laboratory. Standardize and establish new published procedures; evaluate innovative techniques. Develop new assays and new protocols; design formats.
5. Discuss relevant insights about experimental results with Faculty and provide useful recommendations and analysis.
6. Maintain an integral role in the laboratory's meetings, presentations, and publications. Present information on research and laboratory work to others at laboratory meetings, journal clubs, and seminars.
7. Troubleshoot and correct erroneous results or problems with laboratory equipment. Maintain and repair equipment; monitor proper use by personnel.
8. Maintain optimal protocol and assay accuracy by conducting regular quality and reproducibility checks.
9. Assist in preparing, writing, and maintaining fiscal budget. Monitor expenditures and prepare capital expenditure requests; track funding, maintain accurate balance, and resolve any discrepancies.
10. Follow policies and procedures governing the handling of confidential information as defined by Cincinnati Children's mission and applicable laws and regulations. Ensure timeliness, accuracy, availability, and security of information.
11. Perform routine procedures, including the collection and analysis of research data, which may affect decisions regarding future patient care.
12. Provide services in a manner to be regularly and conveniently available to meet the needs of Cincinnati Children's research initiatives as determined by department management and Cincinnati Children's governing body.
13. Maintain currency in field through continuing education, literature and seminars. Implement this knowledge into the Department.
14. Recommend approaches for improvement activities, recommend and perform new processes, collect and measure data, develop processes based on performance, and communicate results.
15. Ensure that work areas are organized and present a safe, accessible, effective and efficient environment. Manage attendance at required Cincinnati Children's training sessions, including radiation safety, laboratory safety, bloodborne pathogens, and OSHA. Comply with Infection Control policies and procedures.
16. Participate in establishing job requirements and goals; perform duties at the desired level of competency.
17. Understand, adhere to, and model Core Standards as defined organizationally and specifically within the department/unit.
18. Perform other duties as assigned.

Qualifications

EDUCATION/EXPERIENCE

Required: PhD, MD, MBBS or equivalent doctoral degree.

Preferred: Preference will be given to applicants who have completed a PhD in a related field, display critical and independent thinking skills, enthusiasm for science, and an ambition to succeed.